Masashi Akiyama Selected Research

Dichlorodiphenyldichloroethane (DDD)

2/2019	Dyschromatosis symmetrica hereditaria and reticulate acropigmentation of Kitamura: An update.
9/2013	Whole-exome sequencing identifies ADAM10 mutations as a cause of reticulate acropigmentation of Kitamura, a clinical entity distinct from Dowling-Degos disease.

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Masashi Akiyama Research Topics

Disease

34	Ichthyosis (Xeroderma) 05/2024 - 11/2003
23	Dermatomyositis (Dermatopolymyositis) 01/2023 - 01/2011
21	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2023 - 02/2014
20	Neoplasms (Cancer) 06/2023 - 06/2008
19	Atopic Dermatitis (Atopic Eczema) 03/2024 - 02/2007
15	Lamellar Ichthyosis (Harlequin Ichthyosis) 08/2015 - 07/2005
14	Myositis (Idiopathic Inflammatory Myopathies) 12/2022 - 07/2012
12	Inflammation (Inflammations) 03/2024 - 01/2008
11	Melanoma (Melanoma, Malignant) 01/2023 - 01/2011
9	Systemic Scleroderma (Systemic Sclerosis) 12/2023 - 07/2013
8	Polymyositis 02/2022 - 06/2013
7	Systemic Lupus Erythematosus (Libman-Sacks Disease) 08/2023 - 03/2015
7	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2023 - 01/2011
7	Epidermolytic Hyperkeratosis (Bullous Congenital Ichthyosiform Erythroderma) 09/2014 - 02/2002
6	Pruritus (Itching) 02/2024 - 01/2008
6	Skin Diseases (Skin Disease) 05/2023 - 03/2007
6	Pemphigus (Pemphigus Vulgaris) 02/2023 - 01/2013
6	Bullous Pemphigoid (Pemphigoid) 11/2018 - 03/2005
6	Ichthyosis Vulgaris (Dominant Ichthyosis Vulgaris) 07/2014 - 02/2007
6	Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa) 11/2012 - 01/2006
5	Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara) 02/2024 - 03/2010
5	Rheumatic Diseases (Rheumatism) 08/2023 - 01/2013
5	Chanarin-Dorfman Syndrome 02/2016 - 11/2003
5	Autoimmune Diseases (Autoimmune Disease) 03/2015 - 03/2007
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2022 - 08/2013
4	Fever (Fevers) 02/2022 - 09/2016
4	Epidermolysis Bullosa 08/2010 - 01/2006
3	Hidradenitis Suppurativa 02/2024 - 06/2021
3	Amyopathic dermatomyositis 01/2023 - 01/2011
3	Erythema 01/2023 - 01/2003
3	Hypersensitivity (Allergy) 01/2023 - 11/2018
3	Netherton Syndrome 01/2023 - 11/2018
3	Neoplasm Metastasis (Metastasis) 10/2022 - 05/2015
3	Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris) 01/2022 - 06/2007
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2021 - 07/2006
3	Dyschromatosis symmetrica hereditaria 1 01/2020 - 03/2014
3	Leg Ulcer 11/2019 - 05/2011
3	Thrombosis (Thrombus) 10/2019 - 11/2009
2	Autistic Disorder (Autism) 02/2024 - 01/2021
2	Hepatitis 02/2024 - 01/2021
2	Eczema 02/2024 - 03/2009
2	Keratosis Linearis with Ichthyosis Congenita and Sclerosing Keratoderma 02/2024 - 01/2020
2	Hyperplasia 12/2023 - 09/2016
2	Cutaneous Tuberculosis (Scrofuloderma) 03/2023 - 01/2023
2	Abscess 03/2023 - 01/2023
2	Dermatitis 01/2023 - 01/2022

Drug/Important Bio-Agent (IBA)

29	AutoantibodiesIBA 08/2023 - 03/2005
27	AntibodiesIBA 12/2023 - 06/2008
21	LipidsIBA 12/2023 - 11/2003
13	Proteins (Proteins, Gene)FDA Link 11/2021 - 07/2003
11	Filaggrin ProteinsIBA 01/2020 - 02/2002
9	Immune Checkpoint InhibitorsIBA 06/2023 - 01/2016
7	dupilumabIBA 12/2023 - 09/2020
7	CytokinesIBA 10/2023 - 01/2020
7	NivolumabIBA 01/2023 - 01/2016
7	Keratins (Keratin)IBA 12/2020 - 02/2002
7	Messenger RNA (mRNA)IBA 11/2020 - 05/2003
6	Biomarkers (Surrogate Marker)IBA 02/2024 - 09/2020
6	Immunoglobulin G (IgG)IBA 10/2023 - 04/2006
6	EnzymesIBA 06/2023 - 06/2013
6	CeramidesIBA 12/2022 - 10/2017
6	DNA (Deoxyribonucleic Acid)IBA 11/2020 - 12/2004
6	Nonsense Codon (Nonsense Mutation)IBA 10/2017 - 12/2006
6	Collagen Type XVIIIBA 02/2011 - 03/2007
5	Immunoglobulin E (IgE)IBA 02/2024 - 07/2012
4	AllergensIBA 02/2024 - 03/2011
4	secukinumabIBA 02/2023 - 06/2018
4	Ligases (Synthetase)IBA 01/2023 - 01/2021
4	Amino Acids FDA Link 03/2014 - 06/2007
3	AcidsIBA 01/2024 - 01/2023
3	Anti-Bacterial Agents (Antibiotics)IBA 03/2023 - 01/2019
3	Interleukin-13IBA 02/2023 - 09/2020
3	IpilimumabIBA 01/2023 - 11/2019
3	pembrolizumabIBA 01/2023 - 04/2020
3	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 12/2022 - 01/2021
3	Collodion (Nitrocellulose)IBA 12/2022 - 11/2013
3	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2021 - 10/2013
3	apremilastIBA 05/2021 - 12/2019
3	SteroidsIBA 01/2020 - 12/2018
3	von Willebrand FactorIBA 10/2019 - 11/2009
3	transcriptional intermediary factor 1IBA 12/2016 - 08/2012
3	Hydroxyurea (Hydrea)FDA LinkGeneric 05/2016 - 05/2011
3	Collagen Type VIIIBA 11/2012 - 04/2006
3	transglutaminase 1IBA 08/2011 - 02/2007
3	AntigensIBA 02/2010 - 04/2006
3	Keratin-10IBA 07/2008 - 12/2004
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 02/2024 - 09/2020
2	pazopanib FDA Link 01/2024 - 10/2017
2	Imiquimod (Aldara)FDA LinkGeneric 12/2023 - 11/2020
2	HydrolasesIBA 12/2023 - 11/2008
2	Janus KinasesIBA 11/2023 - 01/2023
2	Intravenous Immunoglobulins (IVIG)FDA Link 01/2023 - 12/2018
2	Interleukin-22 (IL-22)IBA 01/2023 - 09/2020
2	Thymic Stromal LymphopoietinIBA 01/2023 - 09/2020
2	InterleukinsIBA 01/2023 - 11/2020
2	InterferonsIBA 01/2023 - 05/2022
2	Certolizumab Pegol FDA Link 01/2023 - 06/2017

Therapy/Procedure

22	Therapeutics 01/2023 - 12/2006
3	Blood Component Removal (Apheresis) 01/2023 - 01/2022
2	Radiotherapy 01/2023 - 10/2022